Leveraging its integrated "design-synthesis-quality control" system, Creative Biolabs is overcoming bottlenecks in mRNA ...

By combining Transformer-based sequence modeling with a novel conditional probability strategy, the approach overcomes long-standing trade-offs between maximizing expression metrics and maintaining ...

This article and associated images are based on a poster originally authored by Divya Vemula and Vasundhra Bhandari and presented at ELRIG Drug Discovery 2025 in affiliation with the National ...

While codons (combinations of three nucleotides) may vary in which do what functions, a long-standing rule was that each codon serves one specific purpose. New evidence, however suggests that ...

Abstract: Co-optimizing mRNA sequences for both codon optimality and secondary structure is crucial for producing stable and efficacious mRNA therapeutics. Codon optimization, which adjusts nucleotide ...

Background: Colorectal cancer (CRC) has emerged as a growing global health challenge, while immunotherapy, particularly mRNA-based cancer vaccines, has emerged as a promising approach due to its ...

Users are more prepared to buy than ever before when they arrive at your site from an answer engine. The answer engine optimization industry has been infected by a terrible disease of terms that don’t ...

Microbial systems offer distinct advantages in protein expression, saving costs and time, and offering well-characterized host genetics and ease of scale-up. 2 However, challenges remain in process ...