For almost 60 years, scientists have tried to understand why DNA doesn't replicate wildly and uncontrollably every time a ...
Researchers show that loss of the SPRTN enzyme lets DNA–protein crosslinks accumulate, leak DNA into the cytoplasm, activate ...
Every time a cell divides, it must copy its entire genome so that each daughter cell inherits a complete set of DNA. During that process, enzymes known as polymerases race along the DNA to copy its ...
A research team has identified a new mechanism that controls DNA’s ability to replicate—and thereby a cell’s ability to ...
SAR11 bacteria dominate the world’s oceans by being incredibly efficient, shedding genes to survive in nutrient-poor waters.
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How DNA leakage into the cytoplasm drives Ruijs-Aalfs syndrome
Although DNA is tightly packed and safeguarded within the cell nucleus, it remains continually at risk of damage from normal ...
DNA’s iconic double helix does more than “just” store genetic information. Under certain conditions it can temporarily fold into unusual shapes. Researchers at Umeå University, Sweden, have now shown ...
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