Researchers at the Icahn School of Medicine at Mount Sinai have characterized how cellular senescence—a biological process in ...
Explore the connection between neurodegeneration and cellular senescence in understanding brain structure and ageing.
T cell senescence occurs in the TME, affecting cancer prognosis and immunotherapy efficacy. The TME induces T cell senescence through multiple pathways, including persistent stimulation by ...
Findings from the Living Brain Project reveal how senescence processes involved in early brain development may also shape brain aging ...
After a finite number of divisions, cells simply give up. As each round of replication trims their telomeres—the protective caps at the chromosome ends—those caps eventually become too short to ...
There exists a complex synergistic relationship among cancer, circadian rhythms, and aging: aging is a major risk factor for cancer, disruption of circadian rhythms promotes tumor initiation and ...
These patients can get as many as five different cancers before the age of 70, indicating that in people with normal length telomeres, the telomere tumor suppressor pathway prevents many cancers." ...
Demonstrates how dual-purpose therapeutic targets may address both hepatocellular carcinoma progression and cellular senescence ...
Leaf senescence is a tightly regulated developmental process that directly affects plant productivity and lifespan. Understanding how metabolic signals interact with hormonal pathways to control ...
Scientists are unraveling the role of senescent cells in a common form of epilepsy, and it could point to new treatments.
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