Immune checkpoint inhibitor (ICI) pneumonitis is a potentially life-threatening immune-related adverse event associated with ICI therapy across various malignancies. ICIs enhance antitumour immunity ...

Scientists at the Icahn School of Medicine at Mount Sinai have identified an important immune response that helps explain why ...

For women with higher-risk breast cancer, 3 days of radiotherapy might enhance the immune response to checkpoint inhibitors.

Immune checkpoint inhibitor (ICI) therapy before surgery for hepatocellular carcinoma (HCC) may produce major pathological ...

Immune system activation and activity is regulated through stimulatory or inhibitory ligand-receptor interactions collectively termed immune checkpoints. 1 Stimulatory interactions give the immune ...

Cancer immunotherapy has historically focused on harnessing the ability of T cells to recognize and attack cancer cells. Adaptive immune checkpoint inhibitors (ICIs) unleash tumor-infiltrating ...

Scientists at the Icahn School of Medicine at Mount Sinai have identified an important immune response that helps explain why ...

ImmunityBio, Inc. (NASDAQ: IBRX), a commercial-stage immunotherapy company, today announced that the Saudi Food and Drug Authority (SFDA) has granted accelerated approval of ANKTIVA® (nogapendekin ...

Cell cycle checkpoint-related genes (CCCRGs) are implicated in the development and progression of hepatocellular carcinoma (HCC). However, their precise roles and underlying mechanisms remain ...

Cancer immunotherapy has been a game-changer, but many tumors still find ways to slip past the immune system. New research ...

According to a Phase I study led by researchers at The University of Texas MD Anderson Cancer Center, published in Nature ...