T and B lymphocytes, which are part of a group of immune cells commonly called white blood cells, work together to eliminate foreign invaders in the body such as viruses. However, certain diseases can ...

We welcome new subscribers who have recently joined us. The HDO Welcome Letter outlines the three main things you need to know to get off to a good start. The following is a "quick link" to our live ...

Researchers have developed a technology, heteroduplex oligonucleotide (HDO), that silences certain genes whose high expression levels fuel disease. Adding a specific molecular tag allowed them to ...

This figure illustrates the putative mechanism of Toc-HDO-dependent target RNA gene expression regulation. Double-stranded Toc-HDO is recognized by ANXA5 and CA8. Although its mechanisms are not yet ...

Antisense oligonucleotides (ASOs) are small, single-stranded molecules that can suppress the expression of targeted genes and thereby achieve therapeutic effects. However, many ASO-based drug ...

image: An encapsulated bimetallic Ni-Co alloying strategy is innovatively designed to enhance hydrodeoxygenation performance of biomass derivatives to the corresponding methylated products in water.