AZoLifeSciences on MSN
Deep learning–based codon optimization framework boosts protein expression in E coli
By combining Transformer-based sequence modeling with a novel conditional probability strategy, the approach overcomes ...
A virus relies on the host's translation machinery to replicate itself and become infectious. Translation efficiency ...
This is a summary of: Liu. H. et al. Viral RNA blocks circularization to evade host codon usage control. Nature https://doi.org/10.1038/s41586-025-09809-y (2025).
Living things, from bacteria to humans, depend on a workforce of proteins to carry out essential tasks within their cells. Proteins are chains of amino acids that are strung together according to ...
Analysis of genome-wide codon bias shows that only two parameters effectively differentiate the genome-wide codon bias of 100 eubacterial and archaeal organisms. The first parameter correlates with ...
It has long been assumed that there is only one 'canonical' genetic code, so each word means the same thing to every organism. Now, this paradigm has been challenged by the discovery of large numbers ...
Researchers discover a unique genetic code in Antarctic archaea that encodes a rare amino acid, potentially advancing protein ...
Codon Devices, Inc., the Constructive Biology Company™, announced that it has entered into an agreement with Agrivida Inc. for the discovery, development and commercialization of engineered proteins ...
A virus relies on the host's translation machinery to replicate itself and become infectious. Translation efficiency ...
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