Glutamate receptors, including AMPA and NMDA subtypes, are pivotal mediators of excitatory transmission and plasticity across the mammalian central nervous system. Their regulation, which involves ...

Researchers are testing a new approach to repair early memory loss by protecting brain connections affected in Alzheimer’s ...

Cognitive tasks, such as learning and memory, require rapid changes to proteins at synapses, such as protein synthesis, degradation, and trafficking. How protein post-translational modifications ...

A study mapped genes linked to schizophrenia and uncovered a mechanism that disrupts synaptic plasticity in affected individuals. The researchers showed the role of three proteins in mediating the ...

Researchers have found that a natural aging-related molecule can repair key memory processes affected by Alzheimer’s disease.

As animals experience new things, the connections between neurons, called synapses, strengthen or weaken in response to events and the activity they cause in the brain. Neuroscientists believe that ...

Ageing is not a purely degenerative phenomenon, but a dynamic process involving biological, experiential and environmental factors. This is the result of two different projects conducted at SISSA as ...

For decades, dopamine has been celebrated in neuroscience as the quintessential "reward molecule"—a chemical herald of ...

A longevity-linked metabolite restored key memory processes in Alzheimer’s models, highlighting aging biology as a promising therapeutic target. Singapore ranks among the countries with the longest ...

For much of the 20th century, scientists believed that the adult human brain was largely fixed. According to this view, the ...