Scientists have discovered that the internal shape of tiny drug-delivery particles—called lipid nanoparticles—has a big impact on how well our cells absorb them, paving the way to more efficient ...

“We’ve never had such an in-depth map of the CD1 lipidome available,” said Patricia Barral, an immunologist at King’s College London who was not involved with the work. “It will enable us to start ...

Collaboration between researchers at the University of Geneva, Institut de biologie structurale de Grenoble, and the University of Fribourg has shown how lipids and proteins in cell membranes react in ...

Lipids are fatty compounds that perform a range of essential functions in the body. Phospholipids, steroids, and triglycerides are examples of lipids. Although lipids play an essential role in the ...

Scientists have developed a method for analysing the structure of lipid nanoparticles that could be used to improve vaccine and drug delivery, targeting a wide range of health issues. A team led by ...

LNPs are solid or semi-solid particles at room temperature. They are composed of a lipid core stabilized by surfactants or other agents. This lipid core provides a hydrophobic environment ideal for ...

Schematic illustration showing the classification of lipid‐based nanocarriers (LBNCs) (including liposomes, micelles, nanoemulsions, SLNs/NLCs, LNPs, BLNs, SRLNCs) and their targeted delivery to ...

In silico antibody accessibility analysis indicates that ectodomain epitopes are transiently exposed, while MPER epitopes are virtually always occluded in the pre-fusion trimer.

A review maps high throughput strategies that link automation, microfluidics, and barcoding into a unified pipeline, enabling faster, more predictive lipid nanoparticle development for genetic ...