A newly discovered molecule, OLE, restored the brain's immune cells to a more protective state in Alzheimer's disease models.

Researchers have successfully demonstrated how astroglia—cells that support the functioning of the brain—can be reprogrammed into cells resembling interneurons. The research, published in Science ...

A mechanism underlying neutrophil reprogramming in brain cancers has been uncovered, illuminating potential therapeutic targets to stop their pro-cancer effect. Tumor-infiltrating neutrophils are ...

Cellular reprogramming is the hottest topic in longevity science, with tech titans like Sam Altman investing in it. It's now ...

The lab of Filippo Veglia, Ph.D., at The Wistar Institute has discovered a previously unknown mechanism for how aggressive brain cancers reprogram immune system cells from fighting cancer to enabling ...

Brain metastases are one of the most severe complications of melanoma, the most aggressive type of skin cancer. Researchers at the Institute for Neurosciences (IN), a joint center of the Spanish ...

Scientists at MD Anderson Cancer Center have revealed how ATRX mutations restructure chromatin and activate oncogenic ...

When a neuron ages, it loses synaptic connections with other neurons, it is less able to transmit nerve impulses, and its metabolism is also altered. This process of neuronal ageing — inevitable with ...

Promising mouse studies and billions of dollars in funding are stoking excitement. But we’ve been here before.

A newly discovered molecule, OLE, restored the brain’s immune cells to a more protective state in Alzheimer’s disease models. The treatment reduced the accumulation of toxic plaques and improved ...