Membrane protein targeting and insertion is a fundamental process in cellular biology that ensures proteins are correctly delivered to, and integrated within, the lipid bilayer. Proteins destined for ...

Individual mammalian cells contain billions of protein molecules, which must be synthesized, deployed, and removed with ...

Targeted protein degradation (TPD) is transforming drug discovery by leveraging the cell’s natural protein disposal systems to eliminate disease-causing proteins. Innovators are making rapid and ...

Chronic inflammation occurs when the immune system is stuck in attack-mode, sending cell after cell to defend and repair the body for months or even years. Diseases associated with chronic ...

Scientists at Johns Hopkins have uncovered a surprising new way to influence brain activity by targeting a long-mysterious class of proteins linked to anxiety, schizophrenia, and movement disorders.

Deleting a gene cluster in wheat leads to a new seed variety that could be less harmful to individuals with celiac disease. Researchers from the University of California, Davis (CA, USA), have ...

Protein’s always been a big deal when it comes to health—and for all the right reasons. It builds muscle, repairs tissues, ...

Researchers have identified a single protein whose absence can cripple tumors in mice, slowing their growth and in some cases pushing cancer cells to self-destruct. The work, centered on a molecule ...