Modifications made during metabolic engineering for overproduction of chemicals have network-wide effects on cellular function due to ubiquitous metabolic interactions. These interactions, that make ...

Genetically programming the efficient site-specific incorporation of multiple unnatural amino acids into proteins will facilitate a range of applications from Förster resonance energy transfer (FRET) ...

Simply put, orthogonal validation uses additional methods that provide very different selectivity to the primary method to confirm or refute a finding. All methods are independent approaches that can ...

In many experimental situations the pertinent inferences are made on the basis of orthogonal contrasts among the treatment means (as in 2 n factorial experiments). In this setting a particularly ...