Week 18 is on our doorstep and there are still loads to figure out as it relates to the overall playoff picture. Division titles are still on the line, as well as important races to determine seeding in both conferences,

Get the opening NFL Week 18 odds with point spreads, Over/Unders, and football moneylines for every matchup starting on Jan. 3, 2026.

Week 18 features critical matchups with the NFL playoffs approaching. Here are the odds, spreads and totals for every game.