Patients with mast cell activation disorders safely tolerated doses of four of the COVID-19 vaccines, although there was a relative increase in hypersensitivity and anaphylactic reactions, according ...

Eosinophils and mast cells are two types of immune cells with critical roles in responding to foreign assaults. When these cells do not function properly, several disease outcomes can develop (e.g.

For many patients with diverse and seemingly unrelated symptoms, obtaining an accurate diagnosis can take years of specialist visits and inconclusive tests. Mast cell activation syndrome, a disorder ...

In early 2020, Wynde Dyer walked into the house that would transform her life. The Central California ranch sat on a cul-de-sac of gated homes and glittering aquamarine pools. It boasted private ...

Jasper Therapeutics’ monoclonal antibody briquilimab is effective at preventing mast-cell induced anaphylaxis and asthma in mice, new data suggest. In an oral presentation and two posters at the ...

SAN DIEGO--(BUSINESS WIRE)--Escient Pharmaceuticals, a clinical-stage company advancing novel small molecule therapeutics for the potential treatment of a broad range of neurosensory-inflammatory ...

Known for their role in allergic reactions, mast cells have long been recognised as key players in our immune system. When they encounter allergens, they release chemicals that trigger typical allergy ...

According to an international multicenter study, CD2-negative mast cells are associated with significantly reduced overall survival in patients with SM. Patients with CD2-negative mast cells have ...

Blueprint Medicines’ focus on Ayvakit continues to pay off, which has ample untapped revenue potential in advanced and indolent systemic mastocytosis. Additionally, their pipeline includes other ...