Understanding human gene function in living organisms has long been hampered by fundamental differences between species.

Genetic modification aimed at understanding the function and pathology associated with specific genes is most commonly undertaken in mice, as about 99 percent of human genes have mouse orthologs. 1 ...

In the rapidly advancing field of immuno-oncology research, there has been increasing focus on the utility and optimization of cell humanized mice for translational research. Conventional murine ...

Since the development of the super immunodeficient CIEA NOG mouse® in the early 2000s enabled improved humanized immune system (HIS) mice, HIS models have been widely adopted in immuno-oncology ...

For the first time, scientists have successfully created a type of mouse with a 100% functional human immune system and human-like gut microbiome. This 'humanized' mouse takes the guesswork out of ...

Humanized immune system (HIS) mice are invaluable for advancing preclinical research, with various models available to support lymphoid, myeloid and/or specific cell populations. T and NK cells are ...

Desmoplastic nodular medulloblastoma: A National Cancer Database analysis of patient demographics and survival. A phase 1 study to evaluate the safety and tolerability of BXQ-350, a novel sphingolipid ...

DELRAY BEACH, Fla., April 22, 2025 /PRNewswire/ -- The global Humanized Mouse and Rat Model Market, valued at US$255.8 million in 2024, is forecasted to grow at a robust CAGR of 8.2%, reaching ...