When two defective gene variants combine, normal protein function can sometimes be restored.

A new study reveals that super agers over 80 have a distinct genetic edge. They are much less likely to carry the gene most ...

No gene acts alone: interacting variants and protein partnerships can worsen, mask or even rescue disease risk, demanding ...

Sometimes, in genetics, two wrongs do make a right. A research team has recently shown that two harmful genetic variants, ...

With a tank of zebrafish, Queensland researcher Jean Giacomotto was able to test a never-before seen genetic variant ...

The AHA recommended whole exome or whole genome sequencing as first-line diagnostic tools for mitochondrial diseases.

The new molecules selectively reduced inflammatory signaling in human immune cells without affecting other immune pathways. Treatment with the molecules also reduced inflammation in mice with the ...

Results showed that super agers were 68% less likely to have the destructive APOE-ε4 gene, compared to people with Alzheimer’s in the same age range. They also were 19% less likely to have APOE-ε4 ...

An estimated 3 million Americans have an inflammatory bowel disease (IBD) such as Crohn's disease or ulcerative colitis. But ...

The gene variant posing the greatest genetic risk of late-onset Alzheimer's disease (AD) is called APOE-ε4. A different ...

A whole lot more than just one genetic mutation determines whether and how disease develops. lvcandy/DigitalVision Vectors via Getty Images Genetic inheritance may sound straightforward: One gene ...

By Dr. Priyom Bose, Ph.D. By analyzing bowel movement frequency in more than 268,000 people, researchers uncover how thiamine ...