Dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis is a hallmark of major depressive disorder. A number of studies have shown that this dysregulation is correlated with impaired forebrain ...

The Qiang Laboratory concentrates on using human induced pluripotent stem cell (hiPSC) based technologies to establish in vitro (distinct phenotypical CNS neuronal cultures) and ex vivo (3d forebrain ...

When choosing their behavior in socially difficult situations, anxious people use a less suitable section of the forebrain than people who are not anxious. When choosing their behaviour in socially ...

A brain circuit in the mouse basal forebrain that is involved in perceiving the outside world, connects with and overrides feeding behaviors regulated by the hypothalamus. After fasting for 24 hours ...