Super-enhancers in cancer cells trigger DNA breaks and error-prone repair cycles

A new study shows that cancer damages its own DNA by pushing key genes to work too hard. Researchers found that the most powerful genetic "on switches" in cancer cells, called super-enhancers, drive ...
Drug Target Review

New dual CDK approach tackles drug-resistant breast cancer

Explore new findings on drug-resistant breast cancer and how targeting cell cycle regulators may improve treatment outcomes.

Breast cancer study reveals synergistic effect of CDK2 and CDK4/6 combination therapy

A new preclinical study from researchers at The University of Texas MD Anderson Cancer Center, published in Nature ...

Mapping cancer’s weak spots reveals new precision targets for breast cancer

FAYETTEVILLE, GA, UNITED STATES, January 15, 2026 /EINPresswire.com/ -- Understanding why cancer cells rely on specific ...

New study points to genetic ‘Achilles’ Heel’ in cancer cells

Researchers explained to TPS-IL that the same genetic machinery that allows tumors to grow at extremely high speed may also ...

Active aldehydes drive T cell exhaustion in the tumor microenvironment, finds study

Cancer immunotherapy is a type of cancer treatment that harnesses the immune system to fight cancer cells. The treatment ...
EurekAlert!

Centromere protein I, a cell cycle checkpoint gene, accelerates tumor progression via the hippo pathway and mediates immune escape in hepatocellular carcinoma

Cell cycle checkpoint-related genes (CCCRGs) are implicated in the development and progression of hepatocellular carcinoma ...
University of California

New vulnerability identified in aggressive breast cancer

By targeting proteins used to splice genes, UC San Diego researchers have unlocked a new approach to treating triple-negative ...