A phase 1b study of the anticancer stem cell agent demcizumab (DEM), pemetrexed (PEM), and carboplatin (CARBO) in pts with first-line nonsquamous NSCLC. This is an ASCO Meeting Abstract from the 2014 ...
Cancer stem cells, characterized with self-renewal, differentiation, heterogeneity, plasticity and tumorigenicity, are regulated by intrinsic factors such as signaling pathways, transcription factors, ...
Numerous studies have pointed out that cancer stem cells (CSCs) play an important role in cancer progression, metastasis, relapse, and resistance to therapy. Study of these CSCs can shed light why ...